A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DMPK
Type methylation
Species Homo sapiens
Tissue sperm
Experiment Method Bisulfite pyrosequencing, Luciferase reporter assay
Up/Down Down
Pro/Anti Pro
Funtion Description Bisulfite pyrosequencing was used to quantify average methylation levels of these 10 loci in 162 IVF/ICSI sperm samples (cohort 1) which had led to a pregnancy. Four genes, DMPK, FOXK1, KCNA7, and NCOR2, showed significant negative correlation with patern
Regulation Gene DMPK
Year 2016
Pubmed ID 28171595
Title Paternal age effects on sperm FOXK1 and KCNA7 methylation and transmission into the next generation.
Drug 0
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA