A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name DNMT1
Type methylation
Species Rat Rattus
Tissue spinal cords
Experiment Method RT-PCR
Up/Down Down
Pro/Anti Pro
Funtion Description the genomic DNA methylation level and the activity of DNMTs from OPCs derived from rat spinal cords decreased gradually during aging, and OPCs from 16-month-old rats were characterized by global hypomethylation.
Regulation Gene DNMT1
Year 2019
Pubmed ID 30868493
Title Age-related Changes in the Global DNA Methylation Profile of Oligodendrocyte Progenitor Cells Derived from Rat Spinal Cords.
Drug NA
Disease spinal cord diseases
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA