Details
| Name | DNMT1 |
| Type | methylation |
| Species | Mus musculus |
| Tissue | liver |
| Experiment Method | RT-PCR |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | Dnmt1 loss in postnatal hepatocytes caused global hypomethylation, enhanced DNA damage response, and initiated a senescence state causing a progressive inability to maintain tissue homeostasis and proliferate in response to injury. |
| Regulation Gene | DNMT1 |
| Year | 2016 |
| Pubmed ID | 26999257 |
| Title | DNMT1 is a required genomic regulator for murine liver histogenesis and regeneration. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | 1 |
| Variant | NA |
| High-throughput | GSE67771 |