Details
| Name | DNMT3A |
| Type | methylation |
| Species | Homo sapiens |
| Tissue | Human Skin Fibroblasts |
| Experiment Method | Real-time RT-PCR,Chromatin Immunoprecipitation (ChIP),Luciferase assays,Western-blotting,MS-HRM-PCR,Immunofluorescence and microscopy |
| Up/Down | Up |
| Pro/Anti | NA |
| Funtion Description | Anti-DNMT3A chromatin immunoprecipitation was conducted with nuclear extracts from skin fibroblasts isolated from young and elderly individuals, and showed a higher level of DNMT3A protein binding to the LOXL1 promoter in older cells concomitantly to the |
| Regulation Gene | LOXL1 Promoter |
| Year | 2017 |
| Pubmed ID | 27396912 |
| Title | Methylation of LOXL1 Promoter by DNMT3A in Aged Human Skin Fibroblasts. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |