A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name ER
Type methylation
Species Homo sapiens
Tissue human colon
Experiment Method southern blots;RT-PCR
Up/Down Up
Pro/Anti Pro
Funtion Description We report that CpG island methylation, an epigenetic modification of DNA known to correlate closely with silencing of gene transcription, appears in the oestrogen receptor (ER) gene in a subpopulation of cells which increases as a direct function of age i
Regulation Gene oestrogen
Year 1994
Pubmed ID 7951326
Title Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA