| Name |
ER alpha
|
| Type |
methylation
|
| Species |
Homo sapiens
|
| Tissue |
human right atrium, aorta, internal mammary artery, saphenous vein, coronary atherectomy samples, as well as cultured aortic endothelial cells and smooth muscle cells.
|
| Experiment Method |
Southern blot
|
| Up/Down |
NA
|
| Pro/Anti |
NA
|
| Funtion Description |
An age related increase in ER a gene methylation occurs in the right atrium (range 6 to 19%, R=0.36, P<0.05). Significant levels of ER a methylation were detected in both veins and arteries. In addition, ER a gene methylation appears to be increased in co
|
| Regulation Gene |
ER alpha
|
| Year |
1999
|
| Pubmed ID |
10615426
|
| Title |
Methylation of the estrogen receptor gene is associated with aging and atherosclerosis in the cardiovascular system
|
| Drug |
NA
|
| Disease |
atherosclerosis
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|