| Name |
Bmi1
|
| Type |
gene
|
| Species |
Mus musculus
|
| Tissue |
bone
|
| Experiment Method |
Real-time RT-PCR,Intracellular reactive oxygen species (ROS) Analysis,Western blot
|
| Up/Down |
up
|
| Pro/Anti |
Anti
|
| Funtion Description |
Overexpression of Bmi1 in MSCs exerts anti-aging and antiosteoporosis actions by inactivating p16/p19 signaling and inhibiting oxidative stress, suggesting that these findings might provide a strategy to enhance the functionality of MSCs for use in therap
|
| Regulation Gene |
NA
|
| Year |
2018
|
| Pubmed ID |
30895687
|
| Title |
Bmi1 Overexpression in Mesenchymal Stem Cells Exerts Anti-Aging and Anti-Osteoporosis Effects by Inactivating p16/p19 Signaling And Inhibiting Oxidative Stress
|
| Drug |
NA
|
| Disease |
Osteoporosis
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|