A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name EZH2
Type methylation
Species Homo sapiens
Tissue NA
Experiment Method ChIP-qPCR
Up/Down Down
Pro/Anti Pro
Funtion Description downregulation of EZH2 promotes senescence through two distinct mechanisms.
Regulation Gene CDKN2A
Year 2018
Pubmed ID 29590617
Title Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput GSE109064