Details
| Name | EZH2 promoter |
| Type | methylation |
| Species | Homo sapiens |
| Tissue | primary human embryonic lung fibroblasts |
| Experiment Method | qPCR |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | The histone methyltransferase (HMTase), EZH2, was specifically downregulated in senescent cells. Activated p53 suppressed EZH2 gene expression through repression of the EZH2 gene promoter. This activity of p53 requires intact p53 transactivation and DNA b |
| Regulation Gene | EZH2 |
| Year | 2004 |
| Pubmed ID | 15208672 |
| Title | Activated p53 suppresses the histone methyltransferase EZH2 gene. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |