| Name |
FOXP3
|
| Type |
methylation
|
| Species |
Mus musculus
|
| Tissue |
NA
|
| Experiment Method |
PCR, Flow cytometry assay, Western blot
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
DNA from CD4(+) T cells is hypomethylated in aged mice, which also exhibit increased Treg numbers and FoxP3 expression. Additionally, Treg from aged mice also have greater ability to suppress effector T-cell (Teff) proliferation in vitro than Tregs fr
|
| Regulation Gene |
FoxP3, CD86
|
| Year |
2014
|
| Pubmed ID |
24325345
|
| Title |
Aging is associated with increased regulatory T-cell function.
|
| Drug |
0
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|