Details
| Name | GSTP1 promoter |
| Type | methylation |
| Species | Homo sapiens |
| Tissue | lens |
| Experiment Method | RT-PCR,Western blot assay,Bisulfite-sequencing PCR (BSP) cloning and sequencing,Chromatin immunoprecipitation (CHIP) assays,DNA methyltransferase assay |
| Up/Down | Up |
| Pro/Anti | NA |
| Funtion Description | GSTP1 mRNA and protein levels were significantly reduced in lens epithelium and cortex of ARNC cases versus age-matched controls. The changes corresponded to hypermethylation of the GSTP1 promoter CpG islands. |
| Regulation Gene | GSTP1 |
| Year | 2017 |
| Pubmed ID | 27348130 |
| Title | Aberrant Epigenetic Alterations of Glutathione-S-Transferase P1 in Age-Related Nuclear Cataract. |
| Drug | NA |
| Disease | ARNC |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |