| Name |
GZMH
|
| Type |
methylation
|
| Species |
Homo sapiens
|
| Tissue |
Peripheral blood mononuclear cells
|
| Experiment Method |
qPCR
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
The other known genes with decreased methylation and increased expression in aged CD8+ T cells were the proinflammatory mediators IFNG and CCL5, as well as the cytolysis enzyme granzyme GZMH involved in CD8+ T cells effector functions.
|
| Regulation Gene |
GZMH
|
| Year |
2015
|
| Pubmed ID |
26286994
|
| Title |
Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
1
|
| Variant |
NA
|
| High-throughput |
NA
|