A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name HDAC4
Type methylation
Species Homo sapiens
Tissue LEC
Experiment Method qRT-PCR,Western Blot Assay
Up/Down Down
Pro/Anti NA
Funtion Description In our previous research, the formation and development of age-related cataract (ARC) is associated with DNA hypermethylation of some genes in lens epithelial cells (LECs). This study aimed to investigate the expression profile of DNA methylation- and tra
Regulation Gene DNMT3B, HDAC1, HDAC4, HDAC9, and MBD3
Year 2017
Pubmed ID 27306760
Title Expression Profiling of DNA Methylation and Transcriptional Repression Associated Genes in Lens Epithelium Cells of Age-Related Cataract.
Drug NA
Disease ARC
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA