A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Bmi1
Type gene
Species Mus musculus
Tissue neural
Experiment Method PCR
Up/Down NA
Pro/Anti Anti
Funtion Description Bmi-1 thus prevents the premature senescence of neural stem cells by repressing Ink4a and Arf, but additional pathways must also function downstream of Bmi-1.
Regulation Gene NA
Year 2005
Pubmed ID 15964994
Title Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA