| Name |
hMLH1
|
| Type |
methylation
|
| Species |
Homo sapiens
|
| Tissue |
63 male and 37 female with a mean age of 69.5 6 11.9 (mean 6 SD) years (range 43-99 years).
|
| Experiment Method |
Immunohistochemistry;PCR;Combined bisulfite restriction analysis;
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
When the ages of patients were stratified, the prevalence of aberrant hMLH1 expression and methylation increased significantly with age.The frequency of hMLH1 methylation significantly increased with age. These results suggest that hMLH1 methylation plays
|
| Regulation Gene |
hMLH1
|
| Year |
2001
|
| Pubmed ID |
11668499
|
| Title |
Age-related hypermethylation of the hMLH1 promoter in gastric cancers.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|