Details
| Name | HOPX |
| Type | methylation |
| Species | Homo sapiens |
| Tissue | lung |
| Experiment Method | RT-PCR, RNAi, Western blot, Immunofluorescence |
| Up/Down | Up |
| Pro/Anti | Anti |
| Funtion Description | It turned out that HOPX inhibited tumour cell proliferation rate, migration, and invasion, and, more interestingly, forced expression of HOPX enhanced cellular senescence via activation of oncogenic Ras and the downstream MAPK pathway, which in turn led t |
| Regulation Gene | MDM2, p21, HOPX |
| Year | 2015 |
| Pubmed ID | 25345926 |
| Title | HOPX is methylated and exerts tumour-suppressive function through Ras-induced senescence in human lung cancer. |
| Drug | 5-aza-2-deoxycytidine |
| Disease | lung cancer |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |