A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name HPP1 promoter
Type methylation
Species Homo sapiens
Tissue pancreatic adenocarcinoma
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description Methylation of HPP1 and UCHL1 by COBRA was more prevalent with increasing age (P = 0.005 for HPP1 and P = 0.006 for UCHL1, Student's t test). Similar age-related increases in the methylation of these two genes were found using MSP analysis. There was also
Regulation Gene HPP1
Year 2005
Pubmed ID 15701843
Title Age- and disease-related methylation of multiple genes in nonneoplastic duodenum and in duodenal juice
Drug NA
Disease pancreatic cancer
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA