A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name hTERT
Type methylation
Species Homo sapiens
Tissue Adipose tissue
Experiment Method qRT-pCR, methylation-specific PCR
Up/Down Down
Pro/Anti Pro
Funtion Description In addition, the percentage of senescent cells had significantly decreased and changes in the methylation status of the CpG islands in the hTERT promoter region under treatment with ZnSO4 were seen.
Regulation Gene hTERT
Year 2017
Pubmed ID 29145503
Title Zinc sulfate contributes to promote telomere length extension via increasing telomerase gene expression, telomerase activity and change in the TERT gene promoter CpG island methylation status of human adipose-derived mesenchymal stem cells.
Drug Zinc sulfate
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA