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Details


Name hTERT promoter
Type methylation
Species Homo sapiens
Tissue A549 cells;HEK293 cells;TIG-1 cells
Experiment Method ChIP,qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description In the present study, we demonstrated that TGF-beta-activated kinase 1 (TAK1), originally identified as a mitogen-activated kinase kinase kinase, represses the hTERT core promoter activity in an E-box-independent manner, and it also represses the transcri
Regulation Gene hTERT
Year 2007
Pubmed ID 17325661
Title TAK1 represses transcription of the human telomerase reverse transcriptase gene
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA