| Name |
IGF2R
|
| Type |
methylation
|
| Species |
Mus musculus
|
| Tissue |
autopsied C57BL/6J mice at the ages of 4, 12, 30, 60, and 100 weeks.
|
| Experiment Method |
Bisulfite treatment;PCR and methylation analysis;RT-PCR.
|
| Up/Down |
NA
|
| Pro/Anti |
NA
|
| Funtion Description |
Methylated CpG residues were extended beyond the 3' boundary of de novo methylation sequence of DMR2 in aged mice. Furthermore, the de novo methylation of DMR2 in aged mice was associated with decreased expression of antisense transcript which recruits DM
|
| Regulation Gene |
Igf2r
|
| Year |
2000
|
| Pubmed ID |
10924343
|
| Title |
De novo methylation at intronic CpG islands of Igf2r is associated with decreased expression of antisense RNA in aged mice.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|