Details
| Name | IGFBP7 |
| Type | methylation |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | PCR,ChIP |
| Up/Down | Down |
| Pro/Anti | Anti |
| Funtion Description | epigenetic inactivation of IGFBP7 appears to play a key role in tumorigenesis of CRCs with CIMP by enabling escape from p53-induced senescence. |
| Regulation Gene | IGFBP7 |
| Year | 2010 |
| Pubmed ID | 19638426 |
| Title | IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype. |
| Drug | NA |
| Disease | CRC |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |