A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name BRAF
Type gene
Species Homo sapiens
Tissue NA
Experiment Method Western blotting,Analysis of SA-b-galactosidase activity
Up/Down Up
Pro/Anti pro
Funtion Description Thus, both in vitro and in vivo, BRAFV600E-expressing melanocytes display classical hallmarks of senescence, suggesting that oncogene-induced senescence represents a genuine protective physiological process.
Regulation Gene NA
Year 2005
Pubmed ID 16079850
Title BRAFE600-associated senescence-like cell cycle arrest of human naevi
Drug NA
Disease Melanocytic naevi
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA