Details
| Name | ITGA2B |
| Type | methylation |
| Species | Homo sapiens |
| Tissue | plasma |
| Experiment Method | bisulfite method followed by pyrosequencing,PCR |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | The sum of z-scores for methylations of ASPA and ITGA2B, both of which declined with age, was significantly lower in DS. Subjects with DS were found to be 3.1 (1.5-4.6) years older than their predicted age based on a regression model of the controls. Elev |
| Regulation Gene | ASPA;ITGA2B |
| Year | 2016 |
| Pubmed ID | 27234618 |
| Title | Plasma Amyloid Beta 1-42 and DNA Methylation Pattern Predict Accelerated Aging in Young Subjects with Down Syndrome. |
| Drug | NA |
| Disease | Down Syndrome |
| Environment Factors | NA |
| Circulating | 1 |
| Variant | NA |
| High-throughput | NA |