A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Keap1 promoter
Type methylation
Species Homo sapiens
Tissue eyes
Experiment Method qPCR, Western blot
Up/Down Down
Pro/Anti Pro
Funtion Description A gene specific DNA methylation study was performed in cataractous lenses of different ages, which revealed significantly increased levels of demethylated DNA in the Keap1 promoter with increasing age.These results suggested that demethylation in the Keap
Regulation Gene Keap1
Year 2015
Pubmed ID 25370996
Title Human agerelated cataracts: Epigenetic suppression of the nuclear factor erythroid 2related factor 2mediated antioxidant system
Drug 0
Disease age-related cataract
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA