Details
| Name | Keap1 promoter |
| Type | methylation |
| Species | Homo sapiens |
| Tissue | eyes |
| Experiment Method | RT-qPCR, Western blot |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | Age-related cataracts are a leading cause of blindness. Previously, we have demonstrated the association of the unfolded protein response with various cataractogenic stressors. Similarly, bisulfite genomic DNA sequencing shows that human clear lenses ( |
| Regulation Gene | Keap1 |
| Year | 2014 |
| Pubmed ID | 24746615 |
| Title | Methylglyoxal induces endoplasmic reticulum stress and DNA demethylation in the Keap1 promoter of human lens epithelial cells and age-related cataracts. |
| Drug | 0 |
| Disease | age-related cataract |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |