A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name BRCA1
Type gene
Species Homo sapiens
Tissue blood
Experiment Method PCR,other
Up/Down Down
Pro/Anti Pro
Funtion Description This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large mu
Regulation Gene NA
Year 2018
Pubmed ID 29449545
Title Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA