| Name |
klotho
|
| Type |
methylation
|
| Species |
Mus musculus
|
| Tissue |
prostate
|
| Experiment Method |
Methylation-specific PCR,qTR-pCR, Bisulfite genomic sequencing, Bisulfite pyrosequencing
|
| Up/Down |
Down
|
| Pro/Anti |
Anti
|
| Funtion Description |
KLOTHO was originally identified as an aging-suppressor gene that causes a human aging-like phenotype when tested in KLOTHO-deficient-mice. The results suggested a remarkable inverse relationship between KLOTHO expression and promoter methylation in prost
|
| Regulation Gene |
KLOTHO
|
| Year |
2017
|
| Pubmed ID |
30460073
|
| Title |
Epigenetic suppression of the anti-aging gene KLOTHO in human prostate cancer cell lines.
|
| Drug |
0
|
| Disease |
prostate cancer
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|