A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name klotho promoter
Type methylation
Species Homo sapiens
Tissue anterior lens capsule
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description Decreased mRNA expression of the Klotho gene was reversely correlated with age. IHC results showed that the Klotho was mainly expressed in the cell membrane and cytoplasm of LECs. It was strongly positive in the young adult group (100.0%), with even distr
Regulation Gene Klotho
Year 2015
Pubmed ID 26221880
Title Epigenetic changes of the Klotho gene in age-related cataracts.
Drug NA
Disease age-related cataract
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA