A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name klotho promoter
Type methylation
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description We found significant association between KLOTHO promoter methylation and (Mild cognitive impairment)MCI in the Han Chinese (CpG1: p = 3.77E-06; CpG2: p = 1.91E-07; CpG3: p = 5.83E-07; CpG4: p = 2.23E-05; CpG5: p = 3.03E-06) but not in the Uygur Chinese. H
Regulation Gene KLOTHO
Year 2015
Pubmed ID 26197428
Title Population Difference in the Associations of KLOTH Promoter Methylation with Mild Cognitive Impairment in Xinjiang Uygur and Han Populations
Drug NA
Disease Mild cognitive impairment
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA