| Name |
Lamc2
|
| Type |
methylation
|
| Species |
Rat Rattus
|
| Tissue |
kidneys
|
| Experiment Method |
Western blot,Chromatin immunoprecipitation,MeDIP, PCR
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
the loss of 5mC at silenced laminin genes drives their de-repression during aging, contributing to the age-related decline in renal function.
|
| Regulation Gene |
Lamc2
|
| Year |
2018
|
| Pubmed ID |
29846172
|
| Title |
Chromatin changes trigger laminin genes dysregulation in aging kidneys.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|