A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name LINE-1
Type methylation
Species Homo sapiens
Tissue blood
Experiment Method PCR, Bisulfite, Pyrosequencing
Up/Down Down
Pro/Anti Pro
Funtion Description These studies confirm that repetitive element LINE-1 is significantly demethylated with increasing age and MNC+ frequency.
Regulation Gene NA
Year 2015
Pubmed ID 26196382
Title The Association of LINE-1 Hypomethylation with Age and Centromere Positive Micronuclei in Human Lymphocytes.
Drug 0
Disease NA
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA