A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name LINE-1
Type methylation
Species Homo sapiens
Tissue heart
Experiment Method PCR
Up/Down Down
Pro/Anti Pro
Funtion Description LINE-1 hypomethylation is associated with the risk of CHD in Chinese population. Potential CHD risk factors such as older age, elevated total cholesterol, and diagnosis of diabetes may have impact on global DNA methylation, whereby exerting their effect o
Regulation Gene LINE-1
Year 2014
Pubmed ID 24918913
Title LINE-1 hypomethylation is associated with the risk of coronary heart disease in Chinese population.
Drug 0
Disease coronary heart disease
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA