A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name MECP2
Type methylation
Species Homo sapiens
Tissue Bone marrow
Experiment Method HS-PCR
Up/Down Up
Pro/Anti Pro
Funtion Description MECP2 is a member of a family of proteins that preferentially bind to methylated CpGs. We analyzed the contribution of MECP2 to the physiology of mesenchymal stem cells (MSCs). Partial silencing of MECP2 in human MSCs induced a significant reduction of S-
Regulation Gene null
Year 2010
Pubmed ID 20065105
Title Partial silencing of methyl cytosine protein binding 2 (MECP2) in mesenchymal stem cells induces senescence with an increase in damaged DNA.
Drug 0
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA