A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name METTL3
Type methylation
Species Mus musculus
Tissue cardiac
Experiment Method qPCR
Up/Down Up
Pro/Anti Anti
Funtion Description METTL3-mediated methylation of mRNA on N6-adenosines as a dynamic modification that is enhanced in response to hypertrophic stimuli and is necessary for a normal hypertrophic response in cardiomyocytes,cardiac-specific METTL3 knockout mice exhibit morphol
Regulation Gene METTL3
Year 2019
Pubmed ID 30586742
Title The N6-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA