A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name MGMT promoter
Type methylation
Species Homo sapiens
Tissue centered anterior capsules
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description DNA methylation of genes with altered expression was determined by bisulfite-specific (BSP) PCR. The mRNA levels of 10 DNA repair genes were decreased and the level of 1 DNA repair gene was increased in LECs of ARC patients compared with controls. The pro
Regulation Gene MGMT
Year 2014
Pubmed ID 25847269
Title Expression and methylation of DNA repair genes in lens epithelium cells of age-related cataract
Drug NA
Disease age-related cataract
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA