A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name MLH1 promoter
Type methylation
Species Homo sapiens
Tissue colorectal cancer tissues
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description Tumors of the microsatellite instability phenotype in the older group were associated with MLH1 inactivation (24/29 or 83 percent), MLH1 promoter methylation (18/29 or 62 percent), and proximal location (25/29 or 86 percent), while tumors in the young gro
Regulation Gene MLH1
Year 2005
Pubmed ID 16374936
Title Mechanisms of microsatellite instability in colorectal cancer patients in different age groups
Drug NA
Disease colorectal cancer
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA