A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Msh2 promoter
Type methylation
Species Mus musculus
Tissue NA
Experiment Method RT-PCR
Up/Down Up
Pro/Anti Pro
Funtion Description this additional methylation did not correlate with a further decrease Msh2 mRNA, suggesting that the increase in methylation in old retired breeder might account for further epigenetic changes that could additionally promote the aging process.
Regulation Gene Msh2
Year 2008
Pubmed ID 18461468
Title Msh2 promoter region hypermethylation as a marker of aging-related deterioration in old retired female breeder mice.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA