Details
| Name | BRD7 |
| Type | gene |
| Species | Homo sapiens |
| Tissue | diploid BJ fibroblasts |
| Experiment Method | qRT-PCR |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | BRD7 depletion significantly delays replicative senescence, as these cells continued to actively proliferate while control firefly luciferase (FF) shRNA expressing cells ceased proliferation and stained positive for senescence-associated (SA) B-galactosid |
| Regulation Gene | NA |
| Year | 2010 |
| Pubmed ID | 20660729 |
| Title | Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |