| Name |
HIC-1
|
| Type |
methylation
|
| Species |
Homo sapiens
|
| Tissue |
Samples of all primary cancers including CRCs, metastatic liver lesions, and normal colon and liver tissues
|
| Experiment Method |
Southern Blot;Hybridization Probes;
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
The N33 gene showed partial methylation in normal colon mucosa, which was age-related (r = 0.7; P = 0.003 using regression analysis). Adenomas and cancers showed further hypermethylation at this locus. Similarly, the MYOD gene showed age-related methylati
|
| Regulation Gene |
N33, MYOD, p16, HIC-1, THBS1, and CALCA
|
| Year |
1998
|
| Pubmed ID |
9850084
|
| Title |
Aging and DNA methylation in colorectal mucosa and cancer.
|
| Drug |
NA
|
| Disease |
colorectal cancer
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|