Details
| Name | NKX2-5 promoter |
| Type | methylation |
| Species | Homo sapiens |
| Tissue | normal prostate peripheral zone tissue |
| Experiment Method | qPCR |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | We found a significant increase in promoter methylation to correlate with age for the CpG islands at RARB2 (r = 0.4; P < 0.0001), RASSF1A (r = 0.27; P = 0.01), GSTP1 (r = 0.59; P < 0.0001), NKX2-5 (r = 0.27; P = 0.008), and ESR1 (r = 0.244; P = 0.026). |
| Regulation Gene | NKX2-5 |
| Year | 2007 |
| Pubmed ID | 17606710 |
| Title | Age-Related DNA Methylation Changes in Normal Human Prostate Tissues |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |