| Name |
NRMT1
|
| Type |
methylation
|
| Species |
Mus musculus
|
| Tissue |
liver, skin
|
| Experiment Method |
RT-PCR, Western blot, Cell proliferation assay
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
To demonstrate if complete loss of NRMT1 subsequently resulted in developmental or aging phenotypes, we constructed the first NRMT1 knockout (Nrmt1(-/-)) mouse.The majority of these mice die shortly after birth.However, the ones that survive, exhibit decr
|
| Regulation Gene |
XPD, DDB2, FABP1, ACAA1, TM7SF2, SC5D, APOE, COX5B, NDUFC1, ATP6VOC
|
| Year |
2015
|
| Pubmed ID |
25843235
|
| Title |
NRMT1 knockout mice exhibit phenotypes associated with impaired DNA repair and premature aging.
|
| Drug |
0
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|