A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name OGG1
Type methylation
Species Homo sapiens
Tissue blood leukocytes
Experiment Method pyrosequencing,PCR
Up/Down NA
Pro/Anti NA
Funtion Description We used Cox regression models to examine prospective associations between cancer incidence and both methylation at the baseline visit and methylation rate of changes over time. Baseline OGG1 methylation was associated with higher risk of all-cancer (HR: 1
Regulation Gene CRAT, iNOS, OGG1 and GCR
Year 2016
Pubmed ID 27186424
Title DNA methylation of oxidative stress genes and cancer risk in the Normative Aging Study.
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA