A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p16 promoter
Type methylation
Species Homo sapiens
Tissue breast
Experiment Method Bisulfite, RNA-seq
Up/Down Up
Pro/Anti Anti
Funtion Description Tt seemed likely that the prevention of cellular senescence we observed was driven by p16 promoter hypermethylation and subsequent repression.
Regulation Gene p16
Year 2017
Pubmed ID 29133799
Title Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors.
Drug 0
Disease breast cancer
Environment Factors NA
Circulating NA
Variant NA
High-throughput GSE100209