A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p16 promoter
Type methylation
Species Mus musculus
Tissue colon tissues
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description Old mice had significantly lower genomic DNA methylation compared with young mice at each level of dietary folate (4.5 +/- 0.2, 4.8 +/- 0.1, and 4.9 +/- 0.1 vs. 6.0 +/- 0.1, 5.3 +/- 0.2, and 5.9 +/- 0.2%, in folate-deplete, -replete, and -supplemented gro
Regulation Gene p16
Year 2007
Pubmed ID 17585020
Title Older age and dietary folate are determinants of genomic and p16-specific DNA methylation in mouse colon
Drug NA
Disease NA
Environment Factors folate
Circulating NA
Variant NA
High-throughput NA