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Details


Name C/EBPB
Type gene
Species Homo sapiens
Tissue LNCaP cells
Experiment Method PCR, western blot, Luciferase reporter assays
Up/Down Up
Pro/Anti Pro
Funtion Description We found that C/EBPB expression is negatively regulated by androgen receptor (AR) activity and that treatment of androgen-sensitive cell lines with anti-androgens increases C/EBPB mRNA and protein levels. Our data demonstrate that up-regulation of C/EBPB
Regulation Gene null
Year 2015
Pubmed ID 25772238
Title CCAAT/Enhancer binding protein B controls androgen-deprivation-induced senescence in prostate cancer cells
Drug NA
Disease prostate cancer
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA