A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p16 promoter
Type methylation
Species Mus musculus
Tissue NA
Experiment Method RT-PCR
Up/Down Up
Pro/Anti Pro
Funtion Description In this model a WSD reduces global DNA methylation, whereas aging itself has no affect. Although the epigenetic effect of aging was not strong enough to alter global DNA methylation, changes in promoter-specific methylation and gene expression occurred wi
Regulation Gene p16
Year 2015
Pubmed ID 26244073
Title A lifelong exposure to a Western-style diet, but not aging, alters global DNA methylation in mouse colon.
Drug 0
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA