Details
| Name | p16(INK4a) promoter |
| Type | methylation |
| Species | Homo sapiens |
| Tissue | soft tissue, bone |
| Experiment Method | PCR, Western blot |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | Since p16(INK4a) is also a CDK4 inhibitor, these observations are in line with our results and according to our observations, CDK4 inhibitors obviously induce senescence in adipocytic differentiated tumours, and also in other mesenchymal-malignant neoplas |
| Regulation Gene | p16(INK4a) |
| Year | 2014 |
| Pubmed ID | 24747207 |
| Title | Loss of p16(INK4a) is associated with reduced patient survival in soft tissue tumours, and indicates a senescence barrier. |
| Drug | 5-aza-20-deoxycytide |
| Disease | soft tissue sarcoma (STS) |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |