A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p16INK4A promoter
Type methylation
Species Homo sapiens
Tissue tumor and corresponding noncancerous liver tissue
Experiment Method qPCR
Up/Down Up
Pro/Anti Pro
Funtion Description The frequency of p16INK4A hypermethylation tended to be higher in hepatitis C virus-related tumors (23 of 32, 72%) than in hepatitis B virus-related tumors (6 of 13, 46%; P=0.1). Aberrant methylation of p16INK4A was also related significantly to increasin
Regulation Gene p16INK4A
Year 2004
Pubmed ID 15569978
Title p16INK4A hypermethylation is associated with hepatitis virus infection, age, and gender in hepatocellular carcinoma
Drug NA
Disease hepatocarcinoma
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA