A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name p19
Type methylation
Species Mus musculus
Tissue the femurs and tibias cells of mice
Experiment Method Western Blot Chemiluminescence Reagent;equential precipitation and blotting;Methylation-Specific PCR (MSP)
Up/Down NA
Pro/Anti NA
Funtion Description Mouse p19(Arf) is encoded by the Ink4a-Arf locus, which also specifies a second tumor suppressor protein, the cyclin D-dependent kinase inhibitor p16(Ink4a). We surveyed bone marrow-derived cells from wild-type, Ink4a-Arf-null, or Arf-null mice for their
Regulation Gene NA
Year 2001
Pubmed ID 11481442
Title Differential effects of p19(Arf) and p16(Ink4a) loss on senescence of murine bone marrow-derived preB cells and macrophages.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA