A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name P2RX7
Type methylation
Species Mus musculus
Tissue intestine
Experiment Method RT-PCR
Up/Down Up
Pro/Anti Pro
Funtion Description Aberrant methylation of promoter CpG islands in cancer is associated with silencing of tumor-suppressor genes, and age-dependent hypermethylation in normal appearing mucosa may be a risk factor for human colon cancer. Our findings demonstrate a surprisin
Regulation Gene null
Year 2010
Pubmed ID 20107151
Title Widespread and tissue specific age-related DNA methylation changes in mice.
Drug 0
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA